{"id":107498,"date":"2021-10-04T21:14:49","date_gmt":"2021-10-04T19:14:49","guid":{"rendered":"https:\/\/www.biocoherence.eu\/?page_id=107498"},"modified":"2025-05-20T18:31:14","modified_gmt":"2025-05-20T16:31:14","slug":"extracellular-matrix-health","status":"publish","type":"page","link":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/","title":{"rendered":"Extracellular Matrix Health"},"content":{"rendered":"\n
<\/span>\"Extracellulaire
\n
<\/div>
\n
<\/div>\n

Extracellular matrix Health<\/h2>\n\n\n\n

Tissue protection keeps cells functioning<\/p>\n\n\n\n

<\/div>\n\n\n\n
\n
Signals back and forth between the tissue and the cells<\/a><\/div>\n<\/div>\n<\/div>\n<\/div><\/section>\n<\/div><\/div>\n\n\n\n
<\/div>
\n
<\/div>\n

Extracellular matrix<\/h2>\n\n\n\n

The extracellular matrix (ECM) is a complex network<\/strong> composed of specific proteins (eg collagen, elastin, fibrillin), proteoglycans and glycoproteins. Components of the ECM are linked together to form a structurally stable structure, which contributes to the mechanical properties of tissues. The ECM is also a reservoir of growth factors and bioactive molecules. It is a highly dynamic entity <\/strong>of vital importance that determines and controls the most fundamental behaviors and characteristics of cells, such as proliferation, adhesion, migration, polarity, differentiation and apoptosis.<\/strong><\/p>\n<\/div>\n<\/div><\/section>\n\n\n\n

<\/div>
\n
<\/div>\n

THE SYSTEM OF REGULATION THAT PENETRATES THE WHOLE BODY<\/h4>\n\n\n\n
<\/div>
\n
<\/div>\n

Extracellular matrix<\/h3>\n<\/div>\n<\/div><\/section>\n\n\n\n

The functioning of the cells depends on the direct environment of the cell. This environment of the cells <\/strong>is formed by what we call the extracellular matrix (ECM). However, the ECM is more than just connective tissue, it is also made up of an extensive network of capillaries (called very fine blood vessels, capillaries), ends of nerves of the autonomic nervous system, and fluid.<\/p>\n<\/div>\n\n\n\n

<\/div>
\n
\"\"<\/a><\/figure>\n<\/div><\/div>\n<\/div><\/section>\n\n\n\n
<\/div>
\n
<\/div>\n

<\/p>\n\n\n\n

The processes that take place in this matrix are referred to as matrix regulation<\/strong>, the largest regulatory system that permeates the entire body. The ECM regulation regulates the supply of nutrients<\/strong> to the cells as well as the removal of waste products<\/strong> from the cells. All immune processes take place there as well as processes related to tissue repair.<\/p>\n\n\n\n

It is therefore responsible for all basic functions<\/strong>. Simply put, the extracellular matrix is involved in one way or another in every function and every process in a living body. Under the right conditions, the matrix will react very quickly and as a whole to stimuli. The ECM is connected via the capillary netwo<\/strong>rk to the hormonal system<\/strong> and via the peripheral nerves of the autonomic nervous system to the central nervous system<\/strong>. Since both regulatory systems are interconnected at the level of the brainstem, the higher regulatory centers may also be affected by the ECM.<\/p>\n\n\n\n

<\/p>\n<\/div>\n<\/div><\/section>\n\n\n\n

<\/div>
\n
<\/div>\n
<\/span>\"cancer
\n

<\/p>\n<\/div><\/div>\n<\/div>\n\n\n\n

<\/div>\n

THE EXTRACELLULAR MATRIX DETERMINES THE HEALTH OF CELLS<\/h4>\n\n\n\n
<\/div>
\n
<\/div>\n

Alignment between cells and tissue<\/h3>\n<\/div>\n<\/div><\/section>\n\n\n\n

Communication<\/strong> between the extracellular matrix<\/strong> and the cells<\/strong> is the main task of this control system. This communication concerns the growth and stability of the cell itself. There is mounting evidence that the biochemical and biomechanical properties of the ECM influence the plasticity of cancer cells and vice versa. Mental aging and Alzheimer’s disease are also directly linked to a reduced ability to regenerate in the ECM of nerves.<\/p>\n\n\n\n

Another example is the storage of non-bioavailable minerals<\/strong> such as Calcium, Magnesium or Copper, or toxic heavy metals in tissue cells. This also disrupts the functioning of cells in organs.<\/p>\n\n\n\n

Keeping cells healthy is called ‘remodelling’. These remodeling processes<\/strong> are vital in the homeostasis<\/strong> of the body and allow normal cellular functions. When this process is disrupted, it leads to pathological processes<\/strong> and ultimately to various diseases. the expression of ECM-degrading proteases are very tightly controlled and regulated, when this balance is disturbed, inflammation and various degenerative processes arise.<\/p>\n\n\n\n

The Hair Mineral Analysis<\/strong> is a system analysis that gives a general picture of the state of the ECM in the body. As such, it is an important part of a total system diagnosis<\/strong> because it reflects how and to what extent different disorders have permeated the body.<\/p>\n\n\n\n

WE ARE GLAD TO EXPLAIN HOW AN IN-DEPTH DIAGNOSIS CAN BE MADE<\/strong><\/h2>\n\n\n\n
\n
Read more about the Hair Mineral Analysis<\/a><\/div>\n<\/div>\n<\/div>\n<\/div><\/section>\n\n\n\n
<\/div>
\n
<\/div>\n

We have various analysis methods for you to get an accurate picture of the health of your clients. The questionnaires in the MyHealth Platform provide you with additional tools to make an even better and more targeted diagnosis. Ask us about the options that suit you and your practice.<\/em><\/h2>\n<\/div>\n<\/div><\/section>\n\n\n\n
<\/div>
\n
<\/div>\n

SEE WHICH OTHER REGULATION PROCESSES ARE RESPONSIBLE FOR OUR MENTAL AND PHYSICAL HEALTH <\/strong><\/h2>\n\n\n\n
\n
Back to systems diagnostics<\/a><\/div>\n<\/div>\n<\/div>\n<\/div><\/section>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Extracellular matrix The extracellular matrix (ECM) is a complex network composed of specific proteins (eg collagen, elastin, fibrillin), proteoglycans and glycoproteins. Components of the ECM are linked together to form a structurally stable structure, which contributes to the mechanical properties of tissues. The ECM is also a reservoir of growth factors and bioactive molecules. It […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":107488,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","ocean_post_layout":"","ocean_both_sidebars_style":"","ocean_both_sidebars_content_width":0,"ocean_both_sidebars_sidebars_width":0,"ocean_sidebar":"0","ocean_second_sidebar":"0","ocean_disable_margins":"enable","ocean_add_body_class":"","ocean_shortcode_before_top_bar":"","ocean_shortcode_after_top_bar":"","ocean_shortcode_before_header":"","ocean_shortcode_after_header":"","ocean_has_shortcode":"","ocean_shortcode_after_title":"","ocean_shortcode_before_footer_widgets":"","ocean_shortcode_after_footer_widgets":"","ocean_shortcode_before_footer_bottom":"","ocean_shortcode_after_footer_bottom":"","ocean_display_top_bar":"default","ocean_display_header":"default","ocean_header_style":"","ocean_center_header_left_menu":"0","ocean_custom_header_template":"0","ocean_custom_logo":0,"ocean_custom_retina_logo":0,"ocean_custom_logo_max_width":0,"ocean_custom_logo_tablet_max_width":0,"ocean_custom_logo_mobile_max_width":0,"ocean_custom_logo_max_height":0,"ocean_custom_logo_tablet_max_height":0,"ocean_custom_logo_mobile_max_height":0,"ocean_header_custom_menu":"0","ocean_menu_typo_font_family":"0","ocean_menu_typo_font_subset":"","ocean_menu_typo_font_size":0,"ocean_menu_typo_font_size_tablet":0,"ocean_menu_typo_font_size_mobile":0,"ocean_menu_typo_font_size_unit":"px","ocean_menu_typo_font_weight":"","ocean_menu_typo_font_weight_tablet":"","ocean_menu_typo_font_weight_mobile":"","ocean_menu_typo_transform":"","ocean_menu_typo_transform_tablet":"","ocean_menu_typo_transform_mobile":"","ocean_menu_typo_line_height":0,"ocean_menu_typo_line_height_tablet":0,"ocean_menu_typo_line_height_mobile":0,"ocean_menu_typo_line_height_unit":"","ocean_menu_typo_spacing":0,"ocean_menu_typo_spacing_tablet":0,"ocean_menu_typo_spacing_mobile":0,"ocean_menu_typo_spacing_unit":"","ocean_menu_link_color":"","ocean_menu_link_color_hover":"","ocean_menu_link_color_active":"","ocean_menu_link_background":"","ocean_menu_link_hover_background":"","ocean_menu_link_active_background":"","ocean_menu_social_links_bg":"","ocean_menu_social_hover_links_bg":"","ocean_menu_social_links_color":"","ocean_menu_social_hover_links_color":"","ocean_disable_title":"default","ocean_disable_heading":"default","ocean_post_title":"","ocean_post_subheading":"","ocean_post_title_style":"","ocean_post_title_background_color":"","ocean_post_title_background":0,"ocean_post_title_bg_image_position":"","ocean_post_title_bg_image_attachment":"","ocean_post_title_bg_image_repeat":"","ocean_post_title_bg_image_size":"","ocean_post_title_height":0,"ocean_post_title_bg_overlay":0.5,"ocean_post_title_bg_overlay_color":"","ocean_disable_breadcrumbs":"default","ocean_breadcrumbs_color":"","ocean_breadcrumbs_separator_color":"","ocean_breadcrumbs_links_color":"","ocean_breadcrumbs_links_hover_color":"","ocean_display_footer_widgets":"default","ocean_display_footer_bottom":"default","ocean_custom_footer_template":"0","footnotes":""},"class_list":["post-107498","page","type-page","status-publish","hentry","entry","owp-thumbs-layout-horizontal","owp-btn-normal","owp-tabs-layout-horizontal","has-no-thumbnails"],"yoast_head":"\nExtracellular Matrix Health - Biocoherence Nederland<\/title>\n<meta name=\"description\" content=\"The extracellular matrix (ECM) is a complex network composed of specific proteins, proteoglycans and glycoproteins.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Extracellular Matrix Health\" \/>\n<meta property=\"og:description\" content=\"Extracellular matrix Health Tissue protection keeps cells functioning Signals back and forth between the tissue and the cells Extracellular matrix The\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/\" \/>\n<meta property=\"og:site_name\" content=\"Biocoherence Nederland\" \/>\n<meta property=\"article:modified_time\" content=\"2025-05-20T16:31:14+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/05\/Extracellulaire-matrix.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"2498\" \/>\n\t<meta property=\"og:image:height\" content=\"738\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/\",\"url\":\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/\",\"name\":\"Extracellular Matrix Health - Biocoherence Nederland\",\"isPartOf\":{\"@id\":\"https:\/\/www.biocoherence.eu\/en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/05\/Extracellulaire-matrix.webp\",\"datePublished\":\"2021-10-04T19:14:49+00:00\",\"dateModified\":\"2025-05-20T16:31:14+00:00\",\"description\":\"The extracellular matrix (ECM) is a complex network composed of specific proteins, proteoglycans and glycoproteins.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#primaryimage\",\"url\":\"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/05\/Extracellulaire-matrix.webp\",\"contentUrl\":\"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/05\/Extracellulaire-matrix.webp\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.biocoherence.eu\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Systems Diagnostics\",\"item\":\"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Extracellular Matrix Health\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.biocoherence.eu\/en\/#website\",\"url\":\"https:\/\/www.biocoherence.eu\/en\/\",\"name\":\"Biocoherence Nederland\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.biocoherence.eu\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.biocoherence.eu\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.biocoherence.eu\/en\/#organization\",\"name\":\"Biocoherence Nederland\",\"url\":\"https:\/\/www.biocoherence.eu\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.biocoherence.eu\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/07\/cropped-Bicoherence-rood-transparant.webp\",\"contentUrl\":\"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/07\/cropped-Bicoherence-rood-transparant.webp\",\"width\":255,\"height\":45,\"caption\":\"Biocoherence Nederland\"},\"image\":{\"@id\":\"https:\/\/www.biocoherence.eu\/en\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Extracellular Matrix Health - Biocoherence Nederland","description":"The extracellular matrix (ECM) is a complex network composed of specific proteins, proteoglycans and glycoproteins.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/","og_locale":"en_US","og_type":"article","og_title":"Extracellular Matrix Health","og_description":"Extracellular matrix Health Tissue protection keeps cells functioning Signals back and forth between the tissue and the cells Extracellular matrix The","og_url":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/","og_site_name":"Biocoherence Nederland","article_modified_time":"2025-05-20T16:31:14+00:00","og_image":[{"width":2498,"height":738,"url":"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/05\/Extracellulaire-matrix.webp","type":"image\/webp"}],"twitter_misc":{"Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/","url":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/","name":"Extracellular Matrix Health - Biocoherence Nederland","isPartOf":{"@id":"https:\/\/www.biocoherence.eu\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#primaryimage"},"image":{"@id":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#primaryimage"},"thumbnailUrl":"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/05\/Extracellulaire-matrix.webp","datePublished":"2021-10-04T19:14:49+00:00","dateModified":"2025-05-20T16:31:14+00:00","description":"The extracellular matrix (ECM) is a complex network composed of specific proteins, proteoglycans and glycoproteins.","breadcrumb":{"@id":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#primaryimage","url":"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/05\/Extracellulaire-matrix.webp","contentUrl":"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/05\/Extracellulaire-matrix.webp"},{"@type":"BreadcrumbList","@id":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/extracellular-matrix-health\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.biocoherence.eu\/en\/"},{"@type":"ListItem","position":2,"name":"Systems Diagnostics","item":"https:\/\/www.biocoherence.eu\/en\/systems-diagnostics\/"},{"@type":"ListItem","position":3,"name":"Extracellular Matrix Health"}]},{"@type":"WebSite","@id":"https:\/\/www.biocoherence.eu\/en\/#website","url":"https:\/\/www.biocoherence.eu\/en\/","name":"Biocoherence Nederland","description":"","publisher":{"@id":"https:\/\/www.biocoherence.eu\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.biocoherence.eu\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.biocoherence.eu\/en\/#organization","name":"Biocoherence Nederland","url":"https:\/\/www.biocoherence.eu\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.biocoherence.eu\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/07\/cropped-Bicoherence-rood-transparant.webp","contentUrl":"https:\/\/www.biocoherence.eu\/wp-content\/uploads\/2025\/07\/cropped-Bicoherence-rood-transparant.webp","width":255,"height":45,"caption":"Biocoherence Nederland"},"image":{"@id":"https:\/\/www.biocoherence.eu\/en\/#\/schema\/logo\/image\/"}}]}},"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"ocean-thumb-m":false,"ocean-thumb-ml":false,"ocean-thumb-l":false,"woocommerce_thumbnail":false,"woocommerce_single":false,"woocommerce_gallery_thumbnail":false,"dgwt-wcas-product-suggestion":false},"uagb_author_info":{"display_name":"Jan Pieter","author_link":"https:\/\/www.biocoherence.eu\/en\/author\/admin\/"},"uagb_comment_info":0,"uagb_excerpt":"Extracellular matrix The extracellular matrix (ECM) is a complex network composed of specific proteins (eg collagen, elastin, fibrillin), proteoglycans and glycoproteins. Components of the ECM are linked together to form a structurally stable structure, which contributes to the mechanical properties of tissues. The ECM is also a reservoir of growth factors and bioactive molecules. It…","_links":{"self":[{"href":"https:\/\/www.biocoherence.eu\/en\/wp-json\/wp\/v2\/pages\/107498","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocoherence.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.biocoherence.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.biocoherence.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biocoherence.eu\/en\/wp-json\/wp\/v2\/comments?post=107498"}],"version-history":[{"count":0,"href":"https:\/\/www.biocoherence.eu\/en\/wp-json\/wp\/v2\/pages\/107498\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.biocoherence.eu\/en\/wp-json\/wp\/v2\/pages\/107488"}],"wp:attachment":[{"href":"https:\/\/www.biocoherence.eu\/en\/wp-json\/wp\/v2\/media?parent=107498"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}